Greetings From Dr. Emborg and the Team!

What is the first thing that comes to your mind when you think about Parkinson’s disease (PD)? Maybe you know someone with PD and you think about this person, about how she or he shakes or has trouble walking. But, did you know that PD affects the nerves of the heart? And the gut? If your PD friend is not talking as much as he/she used to, remember that as PD progresses it may also affect speech. And swallowing. And mood. Your friend is not alone. After age 60, one in every 100 people is affected with PD.

The goal of our team is to understand and find solutions for PD. We hope that what we learn from our PD research will also help patients with other neurodegenerative disorders. We choose PD as a research platform because of how many people are affected by PD and because, although it is a complex disease, we can model different aspects of PD. We strive to identify neglected issues, discover gaps in knowledge and collaborate with other groups to accelerate the process of bridging findings into the clinic.

Our lab is part of the Wisconsin National Primate Research Center and takes full advantage of the rich resources and highly collaborative nature of the UW-Madison community.

 

If  you would like to learn more about Parkinson’s disease follow these links below:

National Institute of Health
NINDS Parkinson’s Disease Information Page

The Michael J. Fox Foundation
MJF Foundation for Parkinson’s Research Information Page

The Parkinson’s Foundation
Parkinson’s Foundation Homepage

American Parkinson Disease Association- Wisconsin Chapter
APDA Wisconsin Chapter Homepage

 

If you would like to learn more about our friends at the University of Wisconsin follow these links:

Wisconsin National Primate Research Center
Read More about our Facility Here!

UW-Madison Medical Physics
Department of Medical Physics Homepage

UW-Madison Stem Cell and Regenerative Medicine Center
Stem Cell and Regenerative Medicine Center Homepage

UW Health Movement Disorders Clinic
UW Health Provided Information on Movement Disorders

 

What’s New?

Emborg and WNPRC colleague’s article published by Science Translational Medicine highlights the limitations, methods, and ethics faced when producing nonhuman primate models of genetic diseases

Modeling genetic diseases in nonhuman primates through embryonic and germline modification: Considerations and challenges

Read Rachael Lee’s article in the Badger Herald about UW-Madison Researchers discovering how brain cell grafts can reverse motor and mood-related symptoms in monkeys with PD.

UW Researchers develop treatment alleviating Parkinson’s symptoms in monkeys

Read UW news article by Chris Barncard on brain cell grafts and Parkinsonian monkey’s symptoms.

Individualized brain cell grafts reverse Parkinson’s symptoms in monkeys

The National Institute of Health ORIP highlights Dr. Marina Emborg, her WNPRC lab team, and their UW-Madison Colleagues’ advances in detecting heart disease in Parkinson’s and evaluating new therapies that specifically target nerve disease within the human heart:

New Visualization Method Gets to the Heart of Parkinson’s Disease

Read UW news article by Chris Barncard on Vermilyea and colleagues’ report on their CRISPR/Cas9 worktargeting the LRRK2 gene:

Cells carrying Parkinson’s mutation could lead to new model for studying disease

Read UW news article by Chris Barncard on Metzger and Colleagues research on the heart and PD:

Researchers trace Parkinson’s damage in the heart

Read UW news article by Chris Barncard where Jeanette Metzger’s graduate work is highlighted at the 2019 commencement:

Friday ceremony inspires with words from honorary degree recipients

Check out our Research Publications page for more information:

Click here to view our Research Publications page